Publicações

@article{Savi2018,

title = {Phaeophleospora vochysiae Savi & Glienke sp. nov. Isolated from Vochysia divergens Found in the Pantanal, Brazil, Produces Bioactive Secondary Metabolites},

author = {Daiani C. Savi and Khaled A. Shaaban and Francielly Maria Wilke Ramos Gos and Larissa V. Ponomareva and Jon S. Thorson and Chirlei Glienke and Jürgen Rohr},

url = {https://www.nature.com/articles/s41598-018-21400-2},

doi = {10.1038/s41598-018-21400-2},

issn = {2045-2322},

year  = {2018},

date = {2018-01-01},

journal = {Scientific Reports 2018 8:1},

volume = {8},

issue = {1},

pages = {1-10},

publisher = {Nature Publishing Group},

abstract = {Microorganisms associated with plants are highly diverse and can produce a large number of secondary metabolites, with antimicrobial, anti-parasitic and cytotoxic activities. We are particularly interested in exploring endophytes from medicinal plants found in the Pantanal, a unique and widely unexplored wetland in Brazil. In a bio-prospecting study, strains LGMF1213 and LGMF1215 were isolated as endophytes from Vochysia divergens, and by morphological and molecular phylogenetic analyses were characterized as Phaeophleospora vochysiae sp. nov. The chemical assessment of this species reveals three major compounds with high biological activity, cercoscosporin (1), isocercosporin (2) and the new compound 3-(sec-butyl)-6-ethyl-4,5-dihydroxy-2-methoxy-6-methylcyclohex-2-enone (3). Besides the isolation of P. vochysiae as endophyte, the production of cercosporin compounds suggest that under specific conditions this species causes leaf spots, and may turn into a pathogen, since leaf spots are commonly caused by species of Cercospora that produce related compounds. In addition, the new compound 3-(sec-butyl)-6-ethyl-4,5-dihydroxy-2-methoxy-6-methylcyclohex-2-enone showed considerable antimicrobial activity and low cytotoxicity, which needs further exploration.},

keywords = {Antibiotics, Environmental Chemistry, only two Phaeophleospora, Plantaginaceae, Polypodiaceae, Proteaceae and Apocynaceae 11-14 So far},

pubstate = {published},

tppubtype = {article}

}